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Rabbit Anti-Mouse Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Polyclonal Antibody

Name: Rabbit Anti-Mouse Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Polyclonal Antibody
SKU: VD2N775
Rating: 5 (1 reviews)

Cat. No.VD2N775

Product TypeAnimal-targeted Antibodies

Size

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Product Overview

BioVenic rabbit polyclonal antibody is specific for mouse proprotein convertase subtilisin/kexin type 9. It is purified by Protein A Purified . It can be applied to WB, IHC, ICC and IP assays of mouse proprotein convertase subtilisin/kexin type 9.

Specifications

Application WB; IHC; ICC; IP

Clonality Polyclonal

Classification Primary Antibody

Clone Y1N274

Host Rabbit

Target Species Mouse

Species Reactivity Mouse

Specificity Mouse Proprotein Convertase Subtilisin/Kexin Type 9

Isotype IgG

Immunogen Recombinant protein of mouse proprotein convertase subtilisin/kexin type 9

Purification Protein A Purified

Concentration 0.5 mg/mL

Conjugation Unconjugated

Preservative and Stabilizer 0.05% Proclin 300

Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% glycerol

Physical State Liquid

Target Information

Mouse Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a serine protease involved in cholesterol metabolism. It regulates the degradation of the low-density lipoprotein receptor (LDLR) by promoting its lysosomal targeting. PCSK9 plays a crucial role in maintaining cholesterol homeostasis. In mice, this enzyme is essential for proper lipid metabolism and overall cardiovascular health.

Target Mouse Proprotein Convertase Subtilisin/Kexin Type 9

Target Synonym FH3; HCHOLA3; NARC1; Hypercholesterolemia,Autosomal Dominant 3; Neural apoptosis-regulated convertase 1; Proprotein convertase 9; Subtilisin/kexin-like protease PC9

Gene ID 100102

UniProt ID Q80W65

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Kawakami, Ryo, et al. "Development of vaccine for dyslipidemia targeted to a proprotein convertase subtilisin/kexin type 9 (PCSK9) epitope in mice." PloS one 13.2 (2018): e0191895.