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Rabbit Anti-Mouse Programmed Cell Death Protein 1 Ligand 2 (PDL2) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse programmed cell death protein 1 ligand 2. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of mouse programmed cell death protein 1 ligand 2.
Specifications
Target Information
Mouse programmed cell death protein 1 ligand 2 (PD-L2) is a transmembrane glycoprotein of the B7 family, a key mediator of T cell immune regulation. It features a conserved extracellular IgV-IgC domain structure, a single transmembrane segment, and a short cytoplasmic tail critical for structural stability and cell surface anchoring. It localizes to the cell membranes of mouse dendritic cells, macrophages and activated B cells, with negligible levels in resting lymphocytes and non-immune tissues. The protein mediates PD-1 binding and T cell activation suppression, with conserved motifs for receptor interaction and immune checkpoint signaling. Mouse PD-L2 shares core functional domains with mammalian orthologs, and has distinct expression patterns differentiating it from PD-L1.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.