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Rabbit Anti-Mouse Procollagen I N-Terminal Propeptide (PINP) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse procollagen I N-terminal propeptide. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of mouse procollagen I N-terminal propeptide.
Specifications
Target Information
Mouse procollagen I N-terminal propeptide (PINP) is the 140-residue globular extension cleaved from amino-propeptide of type I procollagen by N-proteinases during fibril assembly. The domain contains a cysteine-rich von Willebrand factor type C module and multiple N-linked glycosylation sites, forming disulfide-stabilized trimers that circulate in blood after release. Its triple-helical junction remains non-helical, distinguishing PINP from mature collagen. Antibodies raised against recombinant mouse PINP detect both the intact propeptide and its post-translational variants with negligible cross-reactivity to procollagen III N-propeptide or denatured collagen chains, enabling direct measurement of type I collagen synthesis in mouse serum and tissue extracts.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.