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Rabbit Anti-Mouse Poliovirus Receptor Related Protein 3 (PVRL3) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse poliovirus receptor related protein 3. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse poliovirus receptor related protein 3.
Specifications
Target Information
Mouse poliovirus receptor-related protein 3 (PRR3, nectin-3) is a 83 kDa single-span Ig superfamily adhesin whose three Ig-like domains bridge homophilic or heterophilic contacts with nectin-1 and -2, stabilizing epithelial and synaptic junctions. A solvent-exposed 16-aa "KVE" loop (aa 142-157) within the second IgC domain adopts a β-turn unique among PRR paralogs, presenting a conformational epitope preserved after formalin fixation. Affinity-purified antibodies targeting this loop trace native PRR3 in Sertoli-cell ectoplasmic junctions, hippocampal dendritic spines, and renal tubule epithelia, delivering crisp membrane doublets and single-band specificity on immunoblots with no cross-reaction to PRR1 or PRR2.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.