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Rabbit Anti-Mouse Phospholipase A2 Calcium Independent (iPLA2) Polyclonal Antibody

Cat. No.VD1N463

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for mouse phospholipase A2 calcium independent. It is affinity purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse phospholipase A2 calcium independent.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone A12N15
Host Rabbit
Target Species Mouse
Species Reactivity Mouse
Specificity Mouse Phospholipase A2 Calcium Independent
Isotype IgG
Immunogen Recombinant protein of mouse phospholipase A2 calcium independent
Purification Protein A Purified
Concentration 0.22 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% Glycerol
Physical State Liquid

Target Information

Mouse phospholipase A2, calcium-independent (iPLA2) is an enzyme that catalyzes the hydrolysis of membrane phospholipids, releasing fatty acids and lysophospholipids. It functions independently of calcium, distinguishing it from other PLA2 enzymes. iPLA2 is involved in various cellular processes, including lipid metabolism, signal transduction, and apoptosis. It is expressed in multiple tissues and plays a role in inflammatory responses and cellular stress. As a key regulator of lipid signaling pathways, iPLA2 is an important target for studying cell biology, inflammation, and related diseases.

Target Mouse Phospholipase A2 Calcium Independent
Target Synonym PLA2G6; CaI-PLA2; GVI; INAD1; PNPLA9; Ca2+ Independent PLA2; 85 kDa Calcium-Independent Phospholipase A2; Phospholipase A2 group VI(Cytosolic Calcium-Independent)
Gene ID 66853
UniProt ID Q8BJ56

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 2 years). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Yoda, Emiko, et al. "Group VIB calcium-independent phospholipase A2 (iPLA2γ) regulates platelet activation, hemostasis and thrombosis in mice." PLoS One 9.10 (2014): e109409.
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