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Rabbit Anti-Mouse Palmitoyl Protein Thioesterase 1 (PPT1) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse palmitoyl protein thioesterase 1. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of mouse palmitoyl protein thioesterase 1.
Specifications
Target Information
Mouse palmitoyl protein thioesterase 1 (PPT1) is a 306-residue soluble glycoprotein that removes fatty acyl chains from S-acylated cysteines. Synthesized with a 26-aa signal peptide, the mature 27 kDa enzyme folds into an α/β hydrolase domain with a catalytic triad (Ser115, Asp233, His289) and six N-linked glycans that stabilize a compact dimer. Constitutively expressed in neurons, glia and visceral epithelia, PPT1 localizes to lysosomal lumen via mannose-6-phosphate tagging. Antibodies raised against recombinant full-length mouse PPT1 detect native, glycosylated and proteolytically processed forms with negligible cross-reactivity to PPT2 or other thioesterases, enabling precise immunoblot and immunohistochemical visualization in mouse tissue homogenates and sections.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.