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Rabbit Anti-Mouse Optineurin (OPTN) Polyclonal Antibody

Cat. No.VD2N712

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for mouse optineurin. It is purified by Protein A Purified . It can be applied to WB, IHC, ICC and IP assays of mouse optineurin.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone Y1N211
Host Rabbit
Target Species Mouse
Species Reactivity Mouse
Specificity Mouse Optineurin
Isotype IgG
Immunogen Recombinant protein of mouse optineurin
Purification Protein A Purified
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Mouse Optineurin is a multifunctional protein involved in various cellular processes, including vesicle trafficking, autophagy, and immune responses. It is expressed in neurons and other cell types, where it plays a role in maintaining cellular homeostasis. Optineurin interacts with several proteins to regulate intracellular signaling pathways and is implicated in the pathogenesis of neurodegenerative diseases such as glaucoma and amyotrophic lateral sclerosis (ALS). It also participates in the innate immune response by modulating the activity of NF-κB and other transcription factors. Optineurin is an important target for studying neurobiology and disease mechanisms in mouse models.

Target Mouse Optineurin
Target Synonym NRP; FIP2; GLC1E; HIP7; HYPL; TFIIIA-INTP; Glaucoma 1,Open Angle,E(Adult-Onset); Huntingtin-interacting protein 7; Optic neuropathy-inducing protein; E3-14.7K-interacting protein
Gene ID 71648
UniProt ID Q8K3K8

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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