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Rabbit Anti-Mouse Mucin 1 (MUC1) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse mucin 1. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse mucin 1.
Specifications
Target Information
Mouse mucin 1 (MUC1) is a large type-I trans-membrane glycoprotein carrying a tandem-repeat array of 20-aa PTS sequences heavily O-glycosylated within the extracellular domain. These repeats target the apical surface of ductal epithelia, forming a protective barrier that lubricates and shields plasma membranes from enzymatic and mechanical stress. The cytoplasmic tail contains a conserved YEKV motif that links MUC1 to actin and mediates signal-transduction events. Its highly immunogenic tandem-repeat region presents a unique, species-restricted epitope ideal for antibody generation; anti-MUC1 immunoreagents detect both soluble and membrane-bound forms in milk, serum and tissue sections without cross-reacting with other mucins, providing a precise read-out of epithelial integrity and glycosylation status.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.