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Rabbit Anti-Mouse Mothers Against Decapentaplegic Homolog 2 (Smad2) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse mothers against decapentaplegic homolog 2. It is purified by Protein A Purified . It can be applied to WB, IHC, ICC and IP assays of mouse mothers against decapentaplegic homolog 2.
Specifications
Target Information
Mouse Mothers Against Decapentaplegic Homolog 2 (Smad2) is a key mediator of TGF-β signaling, involved in regulating cell proliferation, differentiation, and apoptosis. It is activated by TGF-β receptor kinases, leading to its phosphorylation and nuclear translocation. In the nucleus, Smad2 forms complexes with other Smads to regulate gene expression. This protein is essential for embryonic development and tissue homeostasis, influencing processes such as organogenesis and immune regulation. Dysregulation of Smad2 is associated with various diseases, including cancer and fibrosis. Smad2 is a critical target for studying TGF-β signaling pathways and their roles in health and disease in mouse models.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.