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Rabbit Anti-Mouse Mitogen Activated Protein Kinase 7 (MAPK7) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse mitogen activated protein kinase 7. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse mitogen activated protein kinase 7.
Specifications
Target Information
Mouse mitogen-activated protein kinase 7 (MAPK7, ERK5) is a 98 kDa dual-specificity kinase whose N-terminal kinase domain phosphorylates Ser/Thr targets, while a unique C-terminal tail binds transcription factors, driving growth and stress responses. A solvent-exposed 18-aa "KVE" loop (aa 475-492) between the activation segment and C-tail folds into a β-hairpin unique among mouse MAPK isoforms, presenting a conformational epitope preserved after phosphorylation and fixation. Affinity-purified antibodies targeting this loop trace native MAPK7 in vascular endothelium, cardiac myocytes, and neuronal nuclei, delivering crisp cytoplasmic/nuclear staining and single-band clarity on immunoblots with no cross-reaction to ERK1 or ERK2.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.