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Rabbit Anti-Mouse Mitochondrial Methionyl tRNA Formyltransferase (MTFMT) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse mitochondrial methionyl tRNA formyltransferase. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse mitochondrial methionyl tRNA formyltransferase.
Specifications
Target Information
Mouse Mitochondrial Methionyl-tRNA Formyltransferase (MTFMT) is a matrix enzyme that formylates mitochondrial methionyl-tRNA using 10-formyltetrahydrofolate, producing the initiator fMet-tRNA necessary for organellar translation. Expressed ubiquitously but enriched in heart, brain, and muscle, MTFMT ensures correct initiation of all thirteen mitochondrial-encoded oxidative-phosphorylation subunits. Loss of MTFMT activity disrupts respiratory-chain assembly and ATP synthesis. As the sole source of mitochondrial translation initiation, MTFMT is an important target for studies of mitochondrial biogenesis, metabolic disorders, and inherited mitochondrial myopathies.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.