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Rabbit Anti-Mouse Matrix Metalloproteinase 20 (MMP20) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse matrix metalloproteinase 20. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of mouse matrix metalloproteinase 20.
Specifications
Target Information
Mouse matrix metalloproteinase 20 (MMP20) is a secreted zinc-dependent endopeptidase of the MMP superfamily, a key mediator of extracellular matrix remodeling. It features a conserved N-terminal signal peptide, a propeptide domain, a catalytic domain with zinc-binding motifs, and a hemopexin-like C-terminal domain critical for structural integrity and substrate specificity. It localizes to mouse dental enamel matrices and developing tooth tissues, with negligible levels in non-dental organs. The protein mediates enamel matrix protein degradation and tooth mineralization, with conserved motifs for substrate binding and enzymatic activation. Mouse MMP20 shares core functional domains with mammalian orthologs, and has distinct substrate selectivity differentiating it from MMP8 and MMP9.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.