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Rabbit Anti-Mouse Matrix Metalloproteinase 14 (MMP14) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse matrix metalloproteinase 14. It is purified by Protein A Purified . It can be applied to WB, IHC, ICC and IP assays of mouse matrix metalloproteinase 14.
Specifications
Target Information
Mouse Matrix Metalloproteinase 14 (MMP-14), also known as Membrane Type 1 Matrix Metalloproteinase (MT1-MMP), is an enzyme that plays a critical role in extracellular matrix remodeling. It is uniquely anchored to the cell membrane, facilitating pericellular degradation of matrix components such as collagen and gelatin. MMP-14 is involved in various physiological processes, including tissue morphogenesis, wound healing, and angiogenesis. Its activity is essential for cell migration and invasion, making it a key factor in cancer progression and metastasis. MMP-14 is an important target for studying tissue dynamics and disease mechanisms in mouse models.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Zarrabi, Kevin, et al. "Inhibition of matrix metalloproteinase 14 (MMP-14)-mediated cancer cell migration." Journal of Biological Chemistry 286.38 (2011): 33167-33177.