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Rabbit Anti-Mouse Lymphocyte Activation Gene 3 (LAG3) Polyclonal Antibody

Cat. No.VD3N495

Product TypeVeterinary Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for mouse lymphocyte activation gene 3. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse lymphocyte activation gene 3.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone C1N246
Host Rabbit
Target Species Mouse
Species Reactivity Mouse
Specificity Mouse Lymphocyte Activation Gene 3
Isotype IgG
Immunogen Recombinant protein of mouse lymphocyte activation gene 3
Purification Purified by Protein A
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Mouse Lymphocyte Activation Gene 3 (LAG3) is an immune checkpoint receptor expressed on T cells, natural killer cells, and regulatory T cells. It binds to major histocompatibility complex class II (MHC II) molecules, inhibiting T cell activation and proliferation. LAG3 plays a crucial role in regulating immune responses, maintaining immune tolerance, and preventing autoimmunity. Its interaction with MHC II contributes to the suppression of excessive immune reactions. LAG3 is an important target for studying immune regulation and developing therapeutic strategies in mouse models.

Target Mouse Lymphocyte Activation Gene 3
Target Synonym CD223; Protein FDC
Gene ID 16768
UniProt ID Q61790

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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