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Rabbit Anti-Mouse Low Density Lipoprotein Receptor (LDLR) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse low density lipoprotein receptor. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse low density lipoprotein receptor.
Specifications
Target Information
Mouse low density lipoprotein receptor (LDLR) is an 83-kDa transmembrane glycoprotein primarily expressed in mouse liver, with detectable levels in adrenal glands and macrophages. It mediates endocytosis of LDL-cholesterol, regulating plasma cholesterol homeostasis by facilitating cellular cholesterol uptake. It binds LDL particles via its extracellular ligand-binding domain, initiating receptor-mediated internalization and cholesterol delivery to cells. Beyond lipid metabolism, it contributes to lipid transport in extrahepatic tissues. As a key regulator of cholesterol homeostasis, mouse LDLR is a critical target for studying hypercholesterolemia, atherosclerosis, and lipid-related metabolic disorders.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.