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Rabbit Anti-Mouse LIM and Calponin Homology Domains Containing Protein 1 (LIMCH1) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse lim and calponin homology domains containing protein 1. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of mouse lim and calponin homology domains containing protein 1.
Specifications
Target Information
Mouse LIM and calponin homology domains containing protein 1 (LCHD1) is a cytoskeletal-associated protein with dual conserved domains, a key regulator of actin cytoskeleton dynamics. It features an N-terminal calponin homology (CH) domain for actin binding, two tandem LIM domains for protein-protein interaction, and a C-terminal tail critical for structural stability and subcellular targeting. It localizes to the cytoplasm and cell cortex of mouse fibroblasts, cardiomyocytes and neuronal cells, with negligible levels in hematopoietic and epithelial tissues. The protein mediates actin filament organization and cell motility modulation, with conserved motifs for binding to cytoskeletal adaptors. Mouse LCHD1 shares core functional domains with mammalian orthologs, and has distinct tissue specificity differentiating it from other CH-LIM family proteins.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.