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Rabbit Anti-Mouse Kidney Injury Molecule 1 (KIM-1) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse kidney injury molecule 1. It is affinity purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse kidney injury molecule 1.
Specifications
Target Information
Mouse Kidney Injury Molecule 1 (KIM-1) is a type I transmembrane protein that is highly expressed in the kidneys, particularly in response to acute kidney injury. It is involved in the repair and regeneration of renal tubular epithelial cells following damage. KIM-1 also plays a role in the internalization and degradation of debris from damaged cells, promoting tissue repair. In mice, this molecule is a useful biomarker for detecting renal injury and monitoring the progression of kidney diseases.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 2 years). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Humphreys, Benjamin D., et al. "Chronic epithelial kidney injury molecule-1 expression causes murine kidney fibrosis." The Journal of clinical investigation 123.9 (2013): 4023-4035.