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Rabbit Anti-Mouse Jagged 1 (JAG1) Polyclonal Antibody

Cat. No.VD2N605

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for mouse jagged 1. It is purified by Protein A Purified . It can be applied to WB, IHC, ICC and IP assays of mouse jagged 1.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone Y1N104
Host Rabbit
Target Species Mouse
Species Reactivity Mouse
Specificity Mouse Jagged 1
Isotype IgG
Immunogen Recombinant protein of mouse jagged 1
Purification Protein A Purified
Concentration 0.32 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Mouse Jagged 1 is a cell surface protein involved in the Notch signaling pathway. It acts as a ligand for Notch receptors, regulating cell fate decisions, proliferation, and differentiation. Jagged 1 is expressed in various tissues and plays a crucial role in embryonic development, angiogenesis, and tissue homeostasis. In mice, this protein is essential for maintaining cellular communication and supporting normal physiological functions.

Target Mouse Jagged 1
Target Synonym CD339; AGS; AHD; AWS; HJ1; JAGL1; Alagille Syndrome; Jagged 1 Protein
Gene ID 16449
UniProt ID Q9QXX0

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Gjølberg, Torleif Tollefsrud, et al. "Antibody blockade of Jagged1 attenuates choroidal neovascularization." Nature Communications 14.1 (2023): 3109.
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