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Rabbit Anti-Mouse Interleukin 8 Receptor Beta (IL8Rb) Polyclonal Antibody

Cat. No.VD3N108

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for mouse interleukin 8 receptor beta. It is purified by Protein A Purified . It can be applied to WB, IHC, ICC and IP assays of mouse interleukin 8 receptor beta.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone Y1N606
Host Rabbit
Target Species Mouse
Species Reactivity Mouse
Specificity Mouse Interleukin 8 Receptor Beta
Isotype IgG
Immunogen mouse interleukin 8 receptor beta
Purification Protein A Purified
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Mouse Interleukin-8 Receptor Beta (IL-8RB), also known as CXCR2, is a G protein-coupled receptor that binds chemokines like CXCL1 and CXCL2. It mediates neutrophil chemotaxis, degranulation, and respiratory burst, playing a crucial role in the innate immune response to infection and inflammation. IL-8RB is expressed on neutrophils, monocytes, and endothelial cells, where it regulates leukocyte migration and activation. As a key regulator of neutrophil function, IL-8RB is an important target for studying immune cell trafficking and potential therapeutic applications in inflammatory diseases.

Target Mouse Interleukin 8 Receptor Beta
Target Synonym CD182; CDw128b; IL8R-B; IL8-RB; CMKAR2; CXCR2; IL8R2; C-X-C chemokine receptor type 2; GRO/MGSA receptor; High affinity interleukin-8 receptor B
Gene ID 12765
UniProt ID P35343

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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