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Rabbit Anti-Mouse Interleukin 6 Receptor (IL6R) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse interleukin 6 receptor. It is purified by Protein A Purified . It can be applied to WB, IHC, ICC and IP assays of mouse interleukin 6 receptor.
Specifications
Target Information
Mouse Interleukin-6 Receptor (IL-6R) is a key component of the IL-6 signaling pathway, mediating the effects of IL-6 on various cell types. It forms a complex with IL-6 and the gp130 receptor, activating downstream signaling pathways that regulate cell proliferation, differentiation, and survival. IL-6R is expressed on immune cells, hepatocytes, and adipocytes, where it plays a crucial role in immune responses, inflammation, and metabolic regulation. As a central regulator of IL-6 signaling, IL-6R is an important target for studying cytokine biology and potential therapeutic applications in inflammatory and autoimmune diseases.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Tsujinaka, Toshimasa, et al. "Interleukin 6 receptor antibody inhibits muscle atrophy and modulates proteolytic systems in interleukin 6 transgenic mice." The Journal of clinical investigation 97.1 (1996): 244-249.
