Get a quote

We're excited to learn more about your project and provide you with a customized quote tailored to your needs. Please fill out the form below, and we'll get back to you as soon as possible.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Rabbit Anti-Mouse Interleukin 6 Receptor (IL6R) Polyclonal Antibody

Cat. No.VD3N197

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for mouse interleukin 6 receptor. It is purified by Protein A Purified . It can be applied to WB, IHC, ICC and IP assays of mouse interleukin 6 receptor.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone Y1N695
Host Rabbit
Target Species Mouse
Species Reactivity Mouse
Specificity Mouse Interleukin 6 Receptor
Isotype IgG
Immunogen Recombinant protein of mouse interleukin 6 receptor
Purification Protein A Purified
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Mouse Interleukin-6 Receptor (IL-6R) is a key component of the IL-6 signaling pathway, mediating the effects of IL-6 on various cell types. It forms a complex with IL-6 and the gp130 receptor, activating downstream signaling pathways that regulate cell proliferation, differentiation, and survival. IL-6R is expressed on immune cells, hepatocytes, and adipocytes, where it plays a crucial role in immune responses, inflammation, and metabolic regulation. As a central regulator of IL-6 signaling, IL-6R is an important target for studying cytokine biology and potential therapeutic applications in inflammatory and autoimmune diseases.

Target Mouse Interleukin 6 Receptor
Target Synonym CD126; gp80; IL6R; IL-6R-1; IL-6R-Alpha; IL6RA; IL-6 receptor subunit alpha; Membrane glycoprotein 80
Gene ID 16194
UniProt ID P22272

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Tsujinaka, Toshimasa, et al. "Interleukin 6 receptor antibody inhibits muscle atrophy and modulates proteolytic systems in interleukin 6 transgenic mice." The Journal of clinical investigation 97.1 (1996): 244-249.
Inquiry Basket