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Rabbit Anti-Mouse Interleukin 4 Receptor (IL4R) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse interleukin 4 receptor. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of mouse interleukin 4 receptor.
Specifications
Target Information
Mouse interleukin 4 receptor (IL-4R) is a transmembrane glycoprotein encoded by the Il4r gene in Mus musculus, mapped to chromosome 7. It belongs to the type I cytokine receptor family, featuring an extracellular ligand-binding domain with conserved cytokine receptor homology regions, a single transmembrane segment and an intracellular signaling domain. It localizes to cell membrane, with ubiquitous expression in mouse immune cells and enrichment in B lymphocytes, T cells, macrophages and mast cells, with low levels in non-immune tissues. The protein mediates intracellular signal cascade initiation upon ligand binding, with conserved motifs critical for dimerization and activation. Mouse IL-4R shares core functional domains with mammalian orthologs, and has distinct binding specificity differentiating it from other cytokine receptor family members.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.