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Rabbit Anti-Mouse Interleukin 1 Receptor Type II (IL1R2) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse interleukin 1 receptor type II. It is affinity purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse interleukin 1 receptor type II.
Specifications
Target Information
Mouse Interleukin 1 Receptor Type II (IL1R2) is a decoy receptor that plays a crucial role in modulating inflammation. It binds to interleukin-1 (IL1), preventing its interaction with the signaling receptor IL-1R1. IL-1R2 is produced by various cell types, including immune and epithelial cells, and acts as a natural inhibitor of IL-1-mediated inflammation. This receptor is a key regulator of immune responses, helping to limit excessive inflammation and tissue damage. IL-1R2 is involved in various inflammatory conditions and serves as an important checkpoint in the immune system.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 2 years). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Slack, Jennifer, et al. "Independent binding of interleukin-1 alpha and interleukin-1 beta to type I and type II interleukin-1 receptors." Journal of Biological Chemistry 268.4 (1993): 2513-2524.