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Rabbit Anti-Mouse Interleukin 1 Alpha (IL1a) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse interleukin 1 alpha. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse interleukin 1 alpha.
Specifications
Target Information
Mouse interleukin-1 alpha (IL-1α) is a 17 kDa pro-inflammatory cytokine that, once released from the cytosol or cleaved by calpain, binds the IL-1 receptor on fibroblasts, endothelial and immune cells, triggering MyD88-dependent NF-κB activation to amplify early inflammation. Its β-trefoil core presents a unique, species-restricted epitope ideal for antibody generation; anti-IL-1α immunoreagents enable quantification of both precursor and mature forms in tissue homogenates, supernatants and fixed sections without cross-reacting with IL-1β or IL-1Ra, providing a precise read-out of damage-associated inflammatory signaling.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.