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Rabbit Anti-Mouse Intercellular Adhesion Molecule 4 (ICAM4) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse intercellular adhesion molecule 4. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of mouse intercellular adhesion molecule 4.
Specifications
Target Information
Mouse intercellular adhesion molecule 4 (ICAM-4, LW blood group) is a 249-residue type I transmembrane glycoprotein whose extracellular Ig-like domain (D1) binds integrins LFA-1 and α4β1, while a single transmembrane helix anchors the protein to erythroid precursors and endothelial cells. A 46-aa cytoplasmic tail lacks signalling motifs but associates with cytoskeletal adaptors. Expressed selectively in fetal liver, adult bone marrow and spleen, ICAM-4 localizes to plasma membrane and extracellular vesicles. Antibodies raised against the Ig-like or cytoplasmic peptide detect native, glycosylated and soluble forms with negligible cross-reactivity to other ICAM family members, enabling selective immunoblot and immunofluorescence analysis in mouse hematopoietic tissue homogenates and cultured erythroid precursors.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.