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Rabbit Anti-Mouse Integrin Beta 6 (ITGb6) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse integrin beta 6. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of mouse integrin beta 6.
Specifications
Target Information
Mouse integrin β6 is an 804-residue type I transmembrane subunit that pairs exclusively with αV to form the αVβ6 heterodimer. Its extracellular region contains a plexin-semaphorin-integrin (PSI) domain, four EGF-like repeats, a β-tail specific to β6, and an 11-residue cytoplasmic tail with a unique TSXXRXRXD motif that recruits kindlin-1. Expressed selectively on epithelial cells of lung, skin and gut, β6 localizes to focal adhesions and the leading edge of wounds. Antibodies raised against the β-tail or cytoplasmic peptide detect native, glycosylated and cleaved forms with negligible cross-reactivity to other β subunits, enabling selective immunoblot and immunohistochemical detection in mouse tissue homogenates and cultured epithelial cells.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.