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Rabbit Anti-Mouse Integrin Alpha V (ITGaV) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse integrin alpha V. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of mouse integrin alpha V.
Specifications
Target Information
Mouse integrin alpha V (ITGAV) is a 150 kDa type-I transmembrane glycoprotein whose seven-bladed β-propeller and thigh/calf domains pair with β1, β3, β5, β6 or β8 subunits to form receptors that recognize RGD motifs in extracellular matrix ligands. A solvent-exposed 14-aa "KVE" loop (aa 200-213) between blades 3 and 4 of the propeller folds into a β-hairpin unique among mouse integrin α-chains, presenting a conformational epitope preserved after ligand binding and fixation. Affinity-purified antibodies targeting this loop trace native ITGAV in vascular endothelium, osteoclast membranes, and fibroblast focal adhesions, delivering crisp surface rings and single-band clarity on immunoblots with no cross-reaction to ITGA5 or ITGB3.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.