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Rabbit Anti-Mouse Insulin Like Growth Factor 2 (IGF2) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse insulin like growth factor 2. It is affinity purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse insulin like growth factor 2.
Specifications
Target Information
Mouse Insulin-like Growth Factor 2 (IGF2) is a member of the insulin family of polypeptide growth factors, playing a critical role in fetal development and growth. It is primarily produced by the liver and other tissues, with high expression during the prenatal period. IGF2 binds to the IGF-1 receptor and the IGF2/Mannose-6-phosphate receptor, promoting cell proliferation, differentiation, and survival. In mice, IGF2 is essential for skeletal myogenesis and is regulated by microRNAs such as miR-125b. It also influences glucose metabolism in adipose tissue, skeletal muscle, and liver.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 2 years). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Devedjian, Jean-Christophe, et al. "Transgenic mice overexpressing insulin-like growth factor-II in β cells develop type 2 diabetes." The Journal of clinical investigation 105.6 (2000): 731-740.