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Rabbit Anti-Mouse Inducible T-Cell Co Stimulator Ligand (ICOSLG) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse inducible T-cell co stimulator ligand. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of mouse inducible T-cell co stimulator ligand.
Specifications
Target Information
Mouse inducible T-cell co-stimulator ligand (ICOSL, B7-H2) is a 309-residue type I transmembrane glycoprotein whose extracellular IgV-IgC domains engage ICOS on activated T-cells. A single transmembrane helix anchors the protein to plasma membrane, while a 47-aa cytoplasmic tail contains proline-rich motifs that bind adaptors. Expressed on B-cells, dendritic cells and inflamed endothelium, ICOSL localizes to lipid rafts and immune synapses. Antibodies raised against the IgV or cytoplasmic peptide detect native, glycosylated and shed forms with negligible cross-reactivity to B7-1 or B7-2, enabling selective immunoblot and immunohistochemical visualization in mouse tissue homogenates and cultured immune cells.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.