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Rabbit Anti-Mouse Inducible T-Cell Co-Stimulator (ICOS) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse inducible T-cell co-stimulator. It is purified by Protein A Purified . It can be applied to WB, IHC, ICC and IP assays of mouse inducible T-cell co-stimulator.
Specifications
Target Information
Mouse Inducible T-Cell Co-Stimulator (ICOS) is a CD28-family receptor expressed on activated T cells. It binds ICOS-L on antigen-presenting cells, amplifying T-cell proliferation, cytokine secretion, and germinal-center formation. ICOS signaling is essential for effective B-cell help and memory T-cell development. As a key checkpoint in adaptive immunity, ICOS is a valuable target for investigating immune modulation and therapeutic strategies in autoimmunity and cancer.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Zhang, Mengmeng, et al. "Inducible T-cell co-stimulator impacts chronic graft-versus-host disease by regulating both pathogenic and regulatory T cells." Frontiers in immunology 9 (2018): 1461.