This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Rabbit Anti-Mouse Hermansky Pudlak Syndrome Protein 4 (HPS4) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse hermansky pudlak syndrome protein 4. It is purified by protein A/G. It can be applied to WB and IHC assays of mouse hermansky pudlak syndrome protein 4.
Specifications
Target Information
Mouse Hermansky Pudlak Syndrome Protein 4 (HPS4) is a cytoplasmic subunit of the biogenesis of lysosome-related organelles complex-3 (BLOC-3), a key mediator of lysosome-related organelle (LRO) biogenesis and trafficking. It features conserved N-terminal and C-terminal interaction domains, a central structural region, and motifs critical for complex assembly and stability. It localizes to the cytoplasm and late endosomes of mouse melanocytes, platelets and lung epithelial cells, with negligible levels in muscle and neuronal tissues. The protein mediates LRO cargo sorting and organelle maturation, with conserved binding sites for HPS1 and other BLOC-3 components. Mouse HPS4 shares core functional domains with mammalian orthologs, and has distinct tissue specificity differentiating it from other HPS family proteins.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.