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Rabbit Anti-Mouse Growth Arrest and DNA Damage Inducible Protein Gamma (GADD45g) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse growth arrest and DNA damage inducible protein gamma. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse growth arrest and DNA damage inducible protein gamma.
Specifications
Target Information
Mouse growth arrest and DNA-damage-inducible protein gamma (GADD45G) is an 18 kDa intrinsically disordered acid blob that clamps onto the active site of PCNA, transiently blocking replicative polymerases while recruiting repair endonucleases. Its N-terminal 33 residues fold into a U-shaped β-hairpin that docks with MTK1 and p38 MAPK, transmitting stress cues without phosphorylation. A solvent-exposed DE-loop (aa 51-65) houses a conformation-specific epitope absent in paralogs GADD45A and GADD45B, enabling polyclonal antibodies to trace nuclear foci, cytoplasmic stress granules, and serum-derived exosomes with single-band specificity on immunoblots.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.