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Rabbit Anti-Mouse Glycoprotein 130 (GP130) Polyclonal Antibody

Cat. No.VD1N232

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for mouse glycoprotein 130. It is affinity purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse glycoprotein 130.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone A3N90
Host Rabbit
Target Species Mouse
Species Reactivity Mouse
Specificity Mouse Glycoprotein 130
Isotype IgG
Immunogen Recombinant protein of mouse glycoprotein 130
Purification Protein A Purified
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% Glycerol
Physical State Liquid

Target Information

Mouse Glycoprotein 130 (GP130) is a transmembrane protein that serves as a common receptor subunit for several cytokines, including interleukin-6 (IL6), leukemia inhibitory factor (LIF), and oncostatin M (OSM). It forms a receptor complex with specific ligand-binding subunits, initiating downstream signaling pathways such as JAK-STAT and MAPK. GP130 is widely expressed in various tissues and plays a crucial role in regulating cell growth, differentiation, and immune responses.

Target Mouse Glycoprotein 130
Target Synonym CDw130; CD130; IL6ST; GP130-RAPS; IR6RB; IL6R-Beta; IR6RB; IR6-RB; Interleukin 6 Signal Transducer; Oncostatin M Receptor; Interleukin-6 Receptor Subunit Beta
Gene ID 16195
UniProt ID Q00560

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 2 years). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Sims, Natalie A., et al. "Glycoprotein 130 regulates bone turnover and bone size by distinct downstream signaling pathways." The Journal of clinical investigation 113.3 (2004): 379-389.
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