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Rabbit Anti-Mouse Glycoprotein 130 (GP130) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse glycoprotein 130. It is affinity purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse glycoprotein 130.
Specifications
Target Information
Mouse Glycoprotein 130 (GP130) is a transmembrane protein that serves as a common receptor subunit for several cytokines, including interleukin-6 (IL6), leukemia inhibitory factor (LIF), and oncostatin M (OSM). It forms a receptor complex with specific ligand-binding subunits, initiating downstream signaling pathways such as JAK-STAT and MAPK. GP130 is widely expressed in various tissues and plays a crucial role in regulating cell growth, differentiation, and immune responses.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 2 years). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Sims, Natalie A., et al. "Glycoprotein 130 regulates bone turnover and bone size by distinct downstream signaling pathways." The Journal of clinical investigation 113.3 (2004): 379-389.