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Rabbit Anti-Mouse Geminin (GMNN) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse geminin. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of mouse geminin.
Specifications
Target Information
Mouse geminin is a nuclear protein with a conserved cysteine-rich coiled-coil domain, serving as a core regulator of DNA replication licensing and cell cycle progression. It features an N-terminal chromatin-binding motif, a central dimerization region critical for protein complex formation, and a C-terminal destruction box linked to cell cycle-dependent degradation. The protein localizes exclusively to the nucleus of mouse somatic and embryonic cells, with dynamic expression levels fluctuating across cell cycle stages. It mediates interactions with replication initiation factors, with conserved structural elements differentiating it from other cell cycle regulatory proteins.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.