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Rabbit Anti-Mouse GATA Binding Protein 1 (GATA1) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse GATA binding protein 1. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of mouse GATA binding protein 1.
Specifications
Target Information
Mouse GATA-binding protein 1 (GATA1) is a 413-residue nuclear transcription factor containing dual zinc-finger domains (Cys-X2-Cys-X17-Cys-X2-Cys) that recognize the consensus motif (A/T)GATA(A/G) in promoter and enhancer regions of erythroid and megakaryocyte-specific genes. The N-terminal finger mediates DNA tethering while the C-terminal finger provides sequence specificity and recruits Friend of GATA cofactors. Expressed exclusively in hematopoietic lineages, GATA1 localizes to euchromatin during differentiation. Antibodies raised against full-length or zinc-finger peptides detect native, phosphorylated and acetylated isoforms with negligible cross-reactivity to GATA2-6, enabling precise immunoblot and immunohistochemical analysis in mouse hematopoietic tissues and cultured erythroid precursors.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.