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Rabbit Anti-Mouse Gastric Intrinsic Factor (GIF) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse gastric intrinsic factor. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of mouse gastric intrinsic factor.
Specifications
Target Information
Mouse gastric intrinsic factor (GIF) is a secreted glycoprotein encoded by the Gif gene in Mus musculus, mapped to chromosome 6. It is predominantly synthesized and secreted by gastric parietal cells, with a molecular weight of approximately 45 kDa and conserved glycosylation sites essential for structural integrity. The protein harbors a specific cobalamin-binding domain that mediates high-affinity binding to vitamin B12, preventing its degradation in the gastrointestinal tract. Mouse GIF shows tissue-restricted expression limited to gastric mucosa, with conserved functional motifs across mammalian orthologs. It contains an N-terminal secretion signal peptide and a C-terminal binding domain, and shares high sequence homology with other rodent GIF orthologs with subtype-specific structural characteristics.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.