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Rabbit Anti-Mouse Free Fatty Acid Receptor 2 (FFAR2) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse free fatty acid receptor 2. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse free fatty acid receptor 2.
Specifications
Target Information
Mouse free fatty acid receptor 2 (FFAR2, GPR43) is a 35-kDa G protein-coupled receptor predominantly expressed in murine intestinal epithelium, immune cells (neutrophils, macrophages), and adipose tissue. It binds short-chain fatty acids (SCFAs, e.g., acetate, propionate) to activate Gαi/Gαq signaling, regulating gut barrier function, immune modulation, and metabolic homeostasis. Critical for murine gut microbiota-host crosstalk, it modulates inflammation, glucose metabolism, and appetite regulation. Dysregulated expression associates with inflammatory bowel disease, obesity, and metabolic syndrome in mouse models, as impaired SCFA signaling disrupts gut-immune-metabolic crosstalk. As a key mediator of microbial metabolite signaling, mouse FFAR2 is a critical target for studying gut-brain-axis biology and developing therapeutics for metabolic and inflammatory disorders.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.