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Rabbit Anti-Mouse Farnesoid X Receptor (FXR) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse farnesoid X receptor. It is purified by Protein A Purified . It can be applied to WB, IHC, ICC and IP assays of mouse farnesoid X receptor.
Specifications
Target Information
Mouse Farnesoid X Receptor (FXR) is a nuclear receptor involved in the regulation of bile acid, lipid, and glucose metabolism. It is expressed in tissues such as the liver, intestine, and kidney, where it binds to bile acids and other ligands to modulate gene expression. FXR activation influences the synthesis, transport, and excretion of bile acids, helping to maintain cholesterol homeostasis. It also impacts lipid metabolism and glucose uptake, making it a key regulator of metabolic processes. FXR is an important target for studying metabolic diseases and developing therapeutic strategies in mouse models.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Cariou, Bertrand, et al. "The farnesoid X receptor modulates adiposity and peripheral insulin sensitivity in mice." Journal of Biological Chemistry 281.16 (2006): 11039-11049.