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Rabbit Anti-Mouse Epidermal Growth Factor Receptor (EGFR) Polyclonal Antibody

Cat. No.VD2N95

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for mouse epidermal growth factor receptor. It is affinity purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse epidermal growth factor receptor.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone A16N2
Host Rabbit
Target Species Mouse
Species Reactivity Mouse
Specificity Mouse Epidermal Growth Factor Receptor
Isotype IgG
Immunogen Recombinant protein of mouse epidermal growth factor receptor
Purification Protein A Purified
Concentration 0.48 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline, pH 7.4, with 50% Glycerol
Physical State Liquid

Target Information

Mouse Epidermal Growth Factor Receptor (EGFR) is a receptor tyrosine kinase involved in cell growth, proliferation, and differentiation. It is expressed in various tissues and binds to epidermal growth factor (EGF) and related ligands, activating intracellular signaling pathways such as the MAPK and PI3K-Akt pathways. EGFR plays a crucial role in maintaining tissue homeostasis and supporting normal development. In mice, this receptor is essential for epithelial cell functions and is implicated in processes such as wound healing and tissue repair.

Target Mouse Epidermal Growth Factor Receptor
Target Synonym ErbB-1; ErbB1; ER1; ERB-B1; MENA; HER1; Erythroblastic Leukemia Viral(v-Erb-B)oncogene Homolog Avian; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1
Gene ID 13649
UniProt ID Q01279

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 2 years). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Schreiber, Alain B., et al. "Biological role of epidermal growth factor-receptor clustering. Investigation with monoclonal anti-receptor antibodies." Journal of Biological Chemistry 258.2 (1983): 846-853.
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