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Rabbit Anti-Mouse Defensin Alpha 4 (DEFa4) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse defensin alpha 4, corticostatin. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of mouse defensin alpha 4, corticostatin.
Specifications
Target Information
Mouse defensin alpha 4, corticostatin (Defa4) is a 3.5 kDa cationic peptide whose three intramolecular disulfides stabilize a triple-stranded β-sheet that inserts into microbial membranes. A solvent-exposed 10-aa "KVE" loop (aa 15-24) between the second and third cysteine bridges folds into a β-hairpin unique among murine α-defensins, presenting a conformational epitope preserved after secretion and fixation. Affinity-purified antibodies targeting this loop trace native Defa4 in Paneth cell granules, small-intestinal crypts, and colonic mucus, delivering crisp apical granules and single-band clarity on immunoblots with no cross-reaction to Defa1 or Defa5.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.