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Rabbit Anti-Mouse Contactin Associated Protein 1 (Caspr) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse contactin associated protein 1. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of mouse contactin associated protein 1.
Specifications
Target Information
Mouse contactin associated protein 1 (CNTNAP1) is a transmembrane adhesion protein encoded by the Cntnap1 gene in Mus musculus, mapped to chromosome 3. It belongs to the neurexin superfamily, featuring conserved extracellular immunoglobulin-like domains, fibronectin type-III repeats, a single transmembrane segment and a cytoplasmic tail. It localizes to neuronal membranes and myelinating glial cells, with tissue-specific expression in mouse brain and spinal cord, with minimal levels in peripheral tissues. The protein mediates cell adhesion and neuronal circuit formation, with conserved motifs for intermolecular interaction and structural stability. Mouse CNTNAP1 shares core functional domains with mammalian orthologs, and has distinct tissue distribution differentiating it from CNTNAP2 and other neurexin family members.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.