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Rabbit Anti-Mouse Cluster of Differentiation 8b (CD8b) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse cluster of differentiation 8b. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse cluster of differentiation 8b.
Specifications
Target Information
Mouse cluster of differentiation 8b (CD8b) is the beta chain of the CD8 co-receptor. It targets binding to the MHC class I α3 domain, stabilizing the T-cell receptor-peptide-MHC complex and initiating Src-family kinase signaling. CD8b is expressed exclusively on cytotoxic T lymphocytes and thymocytes, where its immunoglobulin-like ectodomain provides a unique, species-restricted epitope ideal for antibody generation. Anti-CD8b immunoreagents therefore deliver precise detection of cytolytic T-cell subsets in tissue sections and flow cytometry without cross-reacting with CD8-independent T cells or other immunoglobulin superfamily members.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.