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Rabbit Anti-Mouse Cluster of Differentiation 42b (CD42b) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse cluster of differentiation 42B. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of mouse cluster of differentiation 42B.
Specifications
Target Information
Mouse cluster of differentiation 42b (CD42b) is a transmembrane glycoprotein subunit of the glycoprotein Ib-IX-V complex, a core regulator of platelet adhesion and hemostatic response. It features an N-terminal extracellular leucine-rich repeat domain, a single transmembrane segment, and a cytoplasmic tail critical for intracellular signaling. It localizes exclusively to the plasma membrane of mouse platelets, with negligible expression in non-hematopoietic tissues. The protein mediates platelet-vessel wall interaction via binding to von Willebrand factor, with conserved motifs for stabilizing the glycoprotein Ib-IX-V complex. Mouse CD42b shares core functional domains with mammalian orthologs, and has distinct binding specificity differentiating it from CD41 and CD61.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.