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Rabbit Anti-Mouse Cluster of Differentiation 40 Ligand (CD40L) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse cluster of differentiation 40 ligand. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse cluster of differentiation 40 ligand.
Specifications
Target Information
Mouse cluster of differentiation 40 ligand (CD40L, also CD154) is a 39 kDa type-II trans-membrane glycoprotein that targets CD40 on B-cells, macrophages and dendritic cells. Binding induces trimerization, recruiting TRAF adaptors to activate NF-κB and MAPK cascades that drive immunoglobulin class-switching, germinal-center formation and dendritic-cell maturation. Its TNF-homology domain presents a unique, species-restricted trimeric epitope ideal for antibody generation; anti-CD40L immunoreagents detect membrane-bound and soluble forms in serum, lymphoid tissue and platelet-rich plasma without cross-reacting with other TNF-family ligands, providing a precise read-out of T-helper and platelet activation.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.