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Rabbit Anti-Mouse Cluster of Differentiation 33 (CD33) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse cluster of differentiation 33. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse cluster of differentiation 33.
Specifications
Target Information
Mouse CD33 is a 67-kDa transmembrane glycoprotein that targets sialylated glycans via its N-terminal V-set Ig-like domain. Expressed on myeloid progenitors, microglia and mast cells, it recruits SHP-1/2 phosphatases through cytoplasmic ITIMs, dampening Src and Syk signaling and limiting proliferation. Its short extracellular stalk presents a unique, species-restricted epitope ideal for antibody generation; anti-CD33 clones therefore label myeloid subsets in bone marrow, spleen and brain sections without cross-reacting with other Siglec family members, providing a clean marker for innate immune mapping and leukemic lineage tracking.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.