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Rabbit Anti-Mouse Cluster of Differentiation 276 (CD276) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse cluster of differentiation 276. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of mouse cluster of differentiation 276.
Specifications
Target Information
Mouse cluster of differentiation 276 (CD276), also termed B7-H3, is a 316-residue type I transmembrane glycoprotein of the B7 superfamily. Its extracellular region contains tandem IgV-IgC domains that can be alternatively spliced into 2Ig or 4Ig isoforms, while a short charged cytoplasmic tail lacks classical signaling motifs. Constitutively expressed at low levels on antigen-presenting cells, osteoblasts and vascular endothelium, the protein is markedly up-regulated during immune activation and on select epithelia. Antibodies directed against mouse CD276 selectively bind native extracellular epitopes with minimal cross-reactivity to B7-1, B7-2 or other B7 family members, permitting accurate detection in lymphoid tissues, bone sections and cultured myeloid cells.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.