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Rabbit Anti-Mouse Chordin Like Protein 1 (CHRDL1) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse chordin like protein 1. It is purified by protein A. It can be applied to WB and IHC assays of mouse chordin like protein 1.
Specifications
Target Information
Mouse chordin-like 1 (CHRDL1, Ventroptin) is a 35 kDa secreted BMP antagonist whose two von Willebrand type C domains clamp BMP-4 and BMP-7, modulating neural patterning and eye development. A solvent-exposed 15-aa "KVE" loop (aa 185-199) between the second vWC domain and the C-terminal tail folds into a β-hairpin unique among mouse BMP regulators, presenting a conformational epitope preserved after secretion and fixation. Affinity-purified antibodies targeting this loop trace native CHRDL1 in retinal ganglion cells, cerebellar granule layers, and meningeal basement membranes, delivering crisp extracellular tracks and single-band clarity on immunoblots with no cross-reaction to chordin or twisted gastrulation.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.