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Rabbit Anti-Mouse Chemokine C-C-Motif Receptor 7 (CCR7) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse chemokine C-C-motif receptor 7. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse chemokine C-C-motif receptor 7.
Specifications
Target Information
Mouse chemokine C-C-motif receptor 7 (CCR7) is a 40-kDa G protein-coupled receptor (GPCR) predominantly expressed on mouse T cells, B cells, and dendritic cells (DCs). It binds cognate ligands CCL19 and CCL21, mediating directed migration of immune cells to secondary lymphoid organs (lymph nodes, spleen) and inflamed tissues. This trafficking is critical for antigen presentation, T/B cell activation, and adaptive immune response initiation. It also regulates immune cell survival and lymphoid tissue homeostasis, supporting effective host defense against pathogens. Dysregulated expression impairs immune surveillance and contributes to inflammatory disorders or cancer metastasis. As a key mediator of immune cell trafficking and adaptive immunity, mouse CCR7 is a critical target for studying immunology, inflammatory diseases, and cancer immunotherapy.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.