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Rabbit Anti-Mouse Carbonic Anhydrase IX (CA9) Polyclonal Antibody

Cat. No.VD2N732

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for mouse carbonic anhydrase ix. It is purified by Protein A Purified . It can be applied to WB, IHC, ICC and IP assays of mouse carbonic anhydrase ix.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone Y1N231
Host Rabbit
Target Species Mouse
Species Reactivity Mouse
Specificity Mouse Carbonic Anhydrase IX
Isotype IgG
Immunogen Recombinant protein of mouse carbonic anhydrase ix
Purification Protein A Purified
Concentration 0.72 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Mouse Carbonic Anhydrase IX (CAIX) is an enzyme that catalyzes the reversible hydration of carbon dioxide to bicarbonate and protons. It is predominantly expressed in tissues exposed to low oxygen levels, such as tumors and certain epithelial cells. CAIX plays a crucial role in maintaining intracellular pH balance under hypoxic conditions, which is essential for cell survival and function. Its expression is regulated by hypoxia-inducible factors (HIFs) and is often used as a biomarker for hypoxia in cancer research. CAIX is an important target for studying hypoxic signaling and cancer biology in mouse models.

Target Mouse Carbonic Anhydrase IX
Target Synonym CA-IX; CAIX; MN; pMW1; P54/58N; Carbonic Dehydratase; Renal cell carcinoma-associated antigen G250; RCC-Associated Protein G250; Carbonate dehydratase IX
Gene ID 230099
UniProt ID Q8VHB5

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Takacova, Martina, et al. "Carbonic anhydrase IX-Mouse versus human." International Journal of Molecular Sciences 21.1 (2019): 246.
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