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Rabbit Anti-Mouse Calcium Channel Voltage Dependent R-Type Alpha 1E Subunit (CACNa1E) Polyclonal Antibody

Cat. No.VD3N931

Product TypeVeterinary Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for mouse calcium channel, voltage dependent, R-type, alpha 1E subunit. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse calcium channel, voltage dependent, R-type, alpha 1E subunit.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone C3N44
Host Rabbit
Target Species Mouse
Species Reactivity Mouse
Specificity Mouse Calcium Channel, Voltage Dependent, R-Type, Alpha 1E Subunit
Isotype IgG
Immunogen Recombinant protein of mouse calcium channel, voltage dependent, R-type, alpha 1E subunit
Purification Purified by Protein A
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Mouse R-type voltage-gated calcium channel α1E (CACNA1E) forms the pore of CaV2.3 channels, mediating rapidly inactivating Ca²⁺ currents in neurons, neuroendocrine cells, and myocytes. The subunit activates at modest depolarizations, fine-tuning transmitter release, repetitive firing, and hormone secretion. CACNA1E associates with β, α2δ, and γ subunits for proper trafficking and gating modulation. As a critical regulator of high-threshold Ca²⁺ entry, α1E is a key target for studies of synaptic plasticity, pain signaling, and neuronal excitability.

Target Mouse Calcium Channel, Voltage Dependent, R-Type, Alpha 1E Subunit
Target Synonym BII; CACNL1A6; CACH6; Brain calcium channel II; Calcium channel, L type, alpha-1 polypeptide, isoform 6
Gene ID 12290
UniProt ID Q61290

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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