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Rabbit Anti-Mouse C4 Binding Protein Alpha (C4BPa) Polyclonal Antibody

Cat. No.VD3N595

Product TypeVeterinary Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for mouse C4 binding protein alpha. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse C4 binding protein alpha.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone C1N346
Host Rabbit
Target Species Mouse
Species Reactivity Mouse
Specificity Mouse C4 Binding Protein Alpha
Isotype IgG
Immunogen Recombinant protein of mouse C4 binding protein alpha
Purification Purified by Protein A
Concentration 0.35 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Mouse C4-binding protein alpha (C4BPA) is the main soluble inhibitor of the classical and lectin complement pathways. By binding nascent C4b it blocks assembly of C3 convertase and, together with factor I, catalyzes proteolytic degradation of C4b/C3b, restraining downstream complement amplification. C4BPA is constitutively produced by liver and secreted into plasma, providing systemic control of innate immune activation and tissue damage. Detection of this regulatory protein offers a reliable read-out for complement status in inflammatory, infectious and autoimmune models.

Target Mouse C4 Binding Protein Alpha
Target Synonym C4BP-a; PRP; C4BP; Complement Component 4 Binding Protein,Alpha; Proline-rich protein
UniProt ID P08607

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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